💊 Skullcap

Scutellaria lateriflora
medicinal_herbs perennial
S
☀️ Sun
Full sun to partial shade
💧 Water
Moderate to high
🗺️ Zones
4–8
🪴 Soil Type
Moist, rich loam
🧪 Soil pH
6.0–7.5
💧 Drainage
Moist to wet, well-drained
📏 Spacing
12–18 inches
📐 Height
1–3 feet
📅 Days to Maturity
90–120 days

🍴 Edible Parts

🍽️ Aerial parts (leaves🍽️ stems🍽️ flowers)

🤝 Companions (7)

Synergistic nervine companions
Shared moisture needs, calming garden theme
🤝 Marshmallow
Moisture-loving companions
Pollinator attractors together
🤝 Wood Betony
Traditional nervous-system herb pairing
🤝 Mint
Moist soil compatibility
🤝 Lobelia
Historic herbalist garden pairing

⚠️ Keep Apart (3)

Too dry for skullcap
Prefer drier conditions, incompatible
Drought-tolerant, skullcap needs moisture

💊 Medicinal Uses

Premier nervine tonic and antispasmodic. Rich in baicalin, baicalein, and wogonin — flavonoids that modulate GABA-A receptors. Used for nervous tension, anxiety, insomnia, muscle spasms, and withdrawal from benzodiazepines. Gentle enough for long-term use. Traditionally combined with valerian for sleep.

📜 History & Traditional Uses

Used by Cherokee and other Native American tribes for menstrual issues and nervous conditions. Adopted by 19th-century Eclectic physicians as a primary nervine. Called 'mad-dog skullcap' historically for a reputed (but unproven) use for rabies. Listed in US Pharmacopeia 1863–1916.

📝 Notes

Not to be confused with Chinese skullcap (Scutellaria baicalensis), which has different properties. Harvest aerial parts during early flowering for highest flavonoid content. Spreads by rhizomes in moist conditions. Tolerates partial shade well — excellent woodland-edge herb.